| Primary Identifier | MGI:104670 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 14229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heat shock protein binding activity; peptidyl-prolyl cis-trans isomerase activity; and protein-macromolecule adaptor activity. Acts upstream of or within response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in alcohol dependence; heroin dependence; and major depressive disorder. Orthologous to human FKBP5 (FKBP prolyl isomerase 5). PHENOTYPE: Mice homozygous for a null allele are normal and fertile. Mice homozygous for another knock-out allele exhibit decreased depression-related behavior and increased anxiety-related behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
