Primary Identifier | MGI:88421 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 109791 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme activator activity. Involved in retinoid metabolic process. Acts upstream of or within response to bacterium. Predicted to be located in extracellular region. Is expressed in gut and male reproductive gland or organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CLPS (colipase). PHENOTYPE: Homozygous mutation of this gene results in increased mortality before weaning. Surviving mutants are growth retarded and remain smaller than wild-type into adulthood with decreased body fat, impaired fat absorption, elevated cholesterol, and reduced triglycerides. [provided by MGI curators] |