| Primary Identifier | MGI:1916625 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 224671 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in modulation of chemical synaptic transmission. Acts upstream of or within several processes, including circadian sleep/wake cycle, non-REM sleep; long-term memory; and multicellular organismal-level iron ion homeostasis. Is active in glutamatergic synapse. Is expressed in several structures, including early conceptus; genitourinary system; liver; retina nuclear layer; and telencephalon. Used to study restless legs syndrome. Orthologous to human BTBD9 (BTB domain containing 9). PHENOTYPE: Mice homozygous for a gene trapped allele show hyperactivity, unidirectional circling, sleep disturbances, thermal sensory alterations, increased serum iron levels, altered serotonin metabolism, enhanced long-term potentiation and paired-pulse ratios, and enhanced cued and contextual fear memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
