Primary Identifier | MGI:1928488 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 56399 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables NF-kappaB binding activity. Involved in cellular response to lipopolysaccharide; cellular response to prostaglandin E stimulus; and negative regulation of tumor necrosis factor production. Acts upstream of or within mitotic chromosome condensation. Located in condensed chromosome; female pronucleus; and nuclear matrix. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human AKAP8 (A-kinase anchoring protein 8). PHENOTYPE: Mice homozygous for a gene trap insertion are viable and overtly normal. [provided by MGI curators] |