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Protein Coding Gene : Akap8 A kinase anchor protein 8

Primary Identifier  MGI:1928488 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  56399
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables NF-kappaB binding activity. Involved in cellular response to lipopolysaccharide; cellular response to prostaglandin E stimulus; and negative regulation of tumor necrosis factor production. Acts upstream of or within mitotic chromosome condensation. Located in condensed chromosome; female pronucleus; and nuclear matrix. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human AKAP8 (A-kinase anchoring protein 8).
PHENOTYPE: Mice homozygous for a gene trap insertion are viable and overtly normal. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1200016A02 gene,
  • expressed sequence AA673585,
  • AU015639,
  • MGI:2146969,
  • MGI:1914712,
  • A kinase anchor protein 8,
  • Akap8,
  • MGI:2146780,
  • 1200016A02Rik,
  • expressed sequence AU015639,
  • AKAP95,
  • AA673585

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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