| Primary Identifier | MGI:2445210 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 320997 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable monooxygenase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in skin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 5. Orthologous to human CYP4F22 (cytochrome P450 family 4 subfamily F member 22). PHENOTYPE: Mice homozygous for a null allele exhibit complete neonatal lethality associated with trans-epidermal water loss, persistent periderm, thin lipid lamella, thick corneocytes, and complete loss of acylceramide. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
