| Primary Identifier | MGI:3045293 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 240069 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and metal ion binding activity. Involved in double-strand break repair involved in meiotic recombination; gamete generation; and homologous chromosome pairing at meiosis. Located in nucleus. Is expressed in germ cell of testis; ovary; spermatid; spermatocyte; and testis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2Z. Orthologous to human MORC2 (MORC family CW-type zinc finger 2). PHENOTYPE: Mice homozygous for a null mutation display male and female infertility with failure of chromosomal synapsis, double strand break repair, and recombination in meiosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
