| Primary Identifier | MGI:3576625 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 378460 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase binding activity. Acts upstream of or within integrin-mediated signaling pathway and regulation of neutrophil degranulation. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in central nervous system; reproductive system; and stomach. Orthologous to human PRAM1 (PML-RARA regulated adaptor molecule 1). PHENOTYPE: Homozygous null mice have neutrophils that exhibit decreased adhesion-dependent reactive oxygen intermediate production and degranulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
