| Primary Identifier | MGI:1932118 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 260297 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor regulator activity. Involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA receptor activity. Acts upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Located in synaptic vesicle membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human PRRT1 (proline rich transmembrane protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced mEPSC, reduced LTP, impaired spatial learning, decreased object recognition and increased exploration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
