Primary Identifier | MGI:96231 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 15482 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP hydrolysis activity; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in cell body. Part of zona pellucida receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb segment. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like). PHENOTYPE: Mice homozygous for a null allele exhibit normal male fertility. [provided by MGI curators] |