Primary Identifier | MGI:90676 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 27756 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA catabolic process and spliceosomal tri-snRNP complex assembly. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Lsm1-7-Pat1 complex; Lsm2-8 complex; and nucleus. Predicted to be active in P-body. Orthologous to human LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation. In vitro, blastocysts hatch from the zona pellucida but form irregular outgrowths after 3 days in culture. [provided by MGI curators] |