Primary Identifier | MGI:1915467 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 53761 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cell differentiation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PRRC2A (proline rich coiled-coil 2A). PHENOTYPE: Mice homozygous for a conditional allele activated in oligodendroglial-lineage cells exhibit reduced reduced weight, increased brain weight, enlarged ventricles, hypomyelination, decreased oligodendrocytes, impaired coordination, decreased grip strength, and impaired spatial learning. [provided by MGI curators] |