| Primary Identifier | MGI:104814 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 15937 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including intracellular signal transduction; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and regulation of primary metabolic process. Located in nucleus. Is expressed in brain; head; and placenta. Human ortholog(s) of this gene implicated in T-cell non-Hodgkin lymphoma. Orthologous to human IER3 (immediate early response 3). PHENOTYPE: Homozygotes for null mutations exhibit elevated systemic arterial pressure. Homozygotes for one null mutation also display cardiac hypertrophy. Homozygotes for a second null mutation display increased susceptibility to parasitic infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
