Primary Identifier | MGI:1923698 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 76448 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity and phosphatase binding activity. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in nervous system. Orthologous to human PPP1R18 (protein phosphatase 1 regulatory subunit 18). PHENOTYPE: Mice homozygous for a null allele exhibit spleen hypoplasia, impaired CD4+ T cell homing, increased white blood cell, lymphocyte, and neutrophil, and reduced B and T cell numbers in the lymph nodes, peripheral lymph nodes, and spleen. [provided by MGI curators] |