Primary Identifier | MGI:1289273 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 52040 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein phosphatase 1 binding activity and protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of cardiac muscle cell apoptotic process; negative regulation of mitotic DNA damage checkpoint; and positive regulation of telomere maintenance. Located in chromatin. Part of PTW/PP1 phosphatase complex. Is expressed in central nervous system; early conceptus; oocyte; and retina. Orthologous to human PPP1R10 (protein phosphatase 1 regulatory subunit 10). PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7. [provided by MGI curators] |