Primary Identifier | MGI:1338757 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 19824 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Involved in innate immune response and negative regulation of viral entry into host cell. Acts upstream of or within erythrocyte differentiation. Located in cytoplasm. Is expressed in several structures, including central nervous system; immune system; liver; and ureter. Orthologous to human TRIM10 (tripartite motif containing 10). PHENOTYPE: Mice homozygous for a null allele show prevention of transverse aortic constriction-induced cardiac hypertrophy. [provided by MGI curators] |