| Primary Identifier | MGI:2684881 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 195359 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of protein localization to nucleus; and protein neddylation. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm. Orthologous to human TRIM40 (tripartite motif containing 40). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced antiviral immune responses and decreased susceptibility to viral infection induced morbidity/mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
