| Primary Identifier | MGI:97435 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 17441 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Located in myelin sheath. Is expressed in brain; cerebellum; and dentate gyrus subgranular zone. Human ortholog(s) of this gene implicated in multiple sclerosis; narcolepsy; and optic neuritis. Orthologous to human MOG (myelin oligodendrocyte glycoprotein). PHENOTYPE: While one line of homozygous mutant mice showed resistance to experimental autoimmune encephalomyelitis (EAE), another showed increased susceptibility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
