| Primary Identifier | MGI:1344410 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 24108 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable proteasome binding activity. Involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; response to tumor necrosis factor; and response to type II interferon. Located in cytoplasm and nucleus. Is expressed in alimentary system; aorta; male reproductive gland or organ; olfactory lobe; and thymus. Orthologous to human UBD (ubiquitin D). PHENOTYPE: Mice hompzygous for disruptions in this gene show an increased susceptibility to low doses of endotoxin and increased apoptosis among lymphocytes but are otherwise normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
