| Primary Identifier | MGI:1202713 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 19743 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ammonium channel activity and methylammonium transmembrane transporter activity. Involved in methylammonium transmembrane transport. Acts upstream of or within ammonium transmembrane transport; erythrocyte development; and multicellular organismal-level iron ion homeostasis. Predicted to be located in membrane. Predicted to be part of ankyrin-1 complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cerebral cortex; liver; and spleen. Human ortholog(s) of this gene implicated in Rh deficiency syndrome; hemolytic anemia; and overhydrated hereditary stomatocytosis. Orthologous to human RHAG (Rh associated glycoprotein). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased ammonium and methylammonium transport in red cell ghosts, reduced basal adhesion of red blood cells to endothelial cells, a slight increase in iron levels, and decreased transferrin levels in males. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
