Primary Identifier | MGI:1858219 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 53901 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; locomotion involved in locomotory behavior; and short-term memory. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; immune system; liver; retina; and stomach. Orthologous to human RCAN2 (regulator of calcineurin 2). PHENOTYPE: Mice homozygous for a knock-out alle exhibit decreased body weight and resistance to diet-induced obesity, steatosis, glucose intolerance, and insulin sensitivity. [provided by MGI curators] |