| Primary Identifier | MGI:2386976 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 224814 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ABC-type glutathione S-conjugate transporter activity and ABC-type xenobiotic transporter activity. Predicted to be involved in leukotriene metabolic process; leukotriene transport; and transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in membrane. Orthologous to human ABCC10 (ATP binding cassette subfamily C member 10). PHENOTYPE: Mice homzozygous for a knock-out allele exhibit increased sensitivity to paclitaxel-induced mortality associated with weight loss, decreased white blood cell, and small spleen and thymus cortex due to apoptosis and/or depopulation of lymphoid cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
