Primary Identifier | MGI:1889348 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 57908 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein heterodimerization activity and protein homodimerization activity. Involved in negative regulation of DNA-templated transcription and positive regulation of DNA-templated transcription. Located in nucleus. Is expressed in central nervous system; early conceptus; reproductive system; and urinary system. Orthologous to human ZNF318 (zinc finger protein 318). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced male fertility and altered IgM and IgD levels. Null mutants displayed normal level of circulating B cells with decreased IgD and increased IgM levels. [provided by MGI curators] |