| Primary Identifier | MGI:104857 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 19208 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within negative regulation of thymocyte apoptotic process. Predicted to be located in plasma membrane. Is expressed in thymus and thymus primordium. Orthologous to human PTCRA (pre T cell antigen receptor alpha). PHENOTYPE: Homozygotes for a knock-out allele show thymus hypoplasia, arrested T cell differentiation, decreased DN4 cell number, and increased DN3 T cell number. Homozygotes for a knock-in allele show decreased double-positive T cell count, increased DN3 number, and increased gamma-delta T cell number. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
