| Primary Identifier | MGI:88315 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 12445 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cyclin-dependent protein serine/threonine kinase activity and protein kinase binding activity. Acts upstream of or within several processes, including T cell proliferation; negative regulation of transcription by RNA polymerase II; and regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; eye; and gonad. Orthologous to human CCND3 (cyclin D3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit severe thymus hypoplasia, abnormal thymocyte development, and impaired expansion of immature T lymphocytes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
