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Protein Coding Gene : Usp49 ubiquitin specific peptidase 49
Primary Identifier  MGI:2685391 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  224836
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable histone binding activity and peptidase activity. Predicted to be involved in mRNA splicing, via spliceosome and negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human USP49 (ubiquitin specific peptidase 49).
PHENOTYPE: Homozygous knockout reduces susceptibility to DNA virus infection. [provided by MGI curators]
  • synonyms:
  • ubiquitin specific peptidase 49,
  • Gm545,
  • RIKEN cDNA C330046L10 gene,
  • Usp49,
  • gene model 545, (NCBI),
  • C330046L10Rik
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