| Primary Identifier | MGI:1917780 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 70530 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Located in cell surface. Is active in Schaffer collateral - CA1 synapse; postsynapse; and presynapse. Is expressed in several structures, including central nervous system; esophagus; eye; male reproductive gland or organ; and trigeminal nerve. Used to study autism spectrum disorder. Orthologous to human LRFN2 (leucine rich repeat and fibronectin type III domain containing 2). PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit small spleens, small or no thymi, impaired T cell development, and decreased T cell proliferation in response to mitogen. Mice homozygous for a null allele exhibit impaired early and late phases of erythropoiesis and normocytic erythrocythemia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
