| Primary Identifier | MGI:1923688 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 76438 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable double-stranded RNA binding activity. Involved in several processes, including T cell antigen processing and presentation; T cell receptor signaling pathway; and positive regulation of interleukin-17 production. Predicted to be located in endosome; membrane raft; and plasma membrane. Predicted to be part of protein-containing complex. Is expressed in brain and dorsal grey horn. Orthologous to human RFTN1 (raftlin, lipid raft linker 1). PHENOTYPE: Mice homozygous for null mutations have defects in T cell activation, T cell help to B cells, and Th17 differentation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
