Primary Identifier | MGI:2156020 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 28106 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including positive regulation of endothelial cell proliferation; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in embryo and extraembryonic component. Orthologous to human MYDGF (myeloid derived growth factor). PHENOTYPE: Mice homozygous for a null mutation display normal cardiac and vascular development but develop larger myocardial infactions with reduced angiogenesis and increased scarring. [provided by MGI curators] |