| Primary Identifier | MGI:108417 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 18188 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables growth factor activity. Involved in cell surface receptor signaling pathway via STAT and glial cell-derived neurotrophic factor receptor signaling pathway. Acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway and nerve development. Is active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human NRTN (neurturin). PHENOTYPE: Mice homozygous for disruptions of this gene have drooping, thickened eyelids which are a manifestation of abnormalities in the parasympathetic system. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
