Primary Identifier | MGI:2146901 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 106628 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in epithelial to mesenchymal transition; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in nucleoplasm. Is expressed in several structures, including clavicle; cranium; inner ear; submandibular gland primordium; and trigeminal ganglion. Orthologous to human TRIP10 (thyroid hormone receptor interactor 10). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased insulin-stimulated glucose uptake in adipocytes and decreased circulating glucose levels. Mice homozygous for another knock-out allele exhibit impaired integrin-dependent T-cell trafficking. [provided by MGI curators] |