| Primary Identifier | MGI:2137520 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 65960 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heparin binding activity. Acts upstream of or within several processes, including BMP signaling pathway; negative regulation of osteoblast differentiation; and regulation of BMP signaling pathway. Located in extracellular space. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; sensory organ; and skeleton. Orthologous to human TWSG1 (twisted gastrulation BMP signaling modulator 1). PHENOTYPE: Homozygous null mice appear healthy at birth, but more than half of the progeny fail to thrive and exhibit dwarfism with delayed ossification and immune system. These defects result in premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
