Primary Identifier | MGI:2147003 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 268970 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Acts upstream of or within negative regulation of stress fiber assembly. Predicted to be located in cell junction and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in lower leg bone. Human ortholog(s) of this gene implicated in allergic disease. Orthologous to human ARHGAP28 (Rho GTPase activating protein 28). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal bone length and ossification. [provided by MGI curators] |