Primary Identifier | MGI:1924140 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 76890 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable peptide binding activity. Predicted to be involved in regulation of microtubule-based process. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human MEMO1 (mediator of cell motility 1). PHENOTYPE: Mice homozygous for null alleles display strain background dependent lethality and defects in vasculogenesis or endochondral bone development. Mice homozygous for a floxed allele activated postnatally exhibit a reduced life span, increased insulin sensitivity, small stature, graying hair, alopecia, kyphosis, loss of subcutaneous fat, loss of spermatozoa in the epididymis and increased active vitamin D. [provided by MGI curators] |