| Primary Identifier | MGI:3028579 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 240168 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables guanyl-nucleotide exchange factor activity; kinase binding activity; and small GTPase binding activity. Acts upstream of or within Ras protein signal transduction. Located in perinuclear region of cytoplasm. Part of guanyl-nucleotide exchange factor complex. Is expressed in cerebral cortex ventricular layer; embryo; and thymus primordium. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RASGRP3 (RAS guanyl releasing protein 3). PHENOTYPE: Homozygous mutant mice are viable and fertile with no obvious abnormalities in the kidneys or vasculature. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
