Primary Identifier | MGI:1919942 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 72692 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity. Predicted to be involved in positive regulation of RNA splicing. Is active in synapse. Is expressed in central nervous system and sensory organ. Orthologous to human HNRNPLL (heterogeneous nuclear ribonucleoprotein L like). PHENOTYPE: Mice homozygous for a point mutation in a RNA recognition motif of the gene product have defects in the generation of alternative transcripts normally found in memory T cells. Total CD4+ T cell counts are lower, with a reduction of naïve CD44lo T cells occurring as mice age. [provided by MGI curators] |