| Primary Identifier | MGI:107945 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 12193 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including hemopoiesis; negative regulation of cell differentiation; and positive regulation of mRNA catabolic process. Acts upstream of or within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; early conceptus; eye; genitourinary system; and immune system. Orthologous to human ZFP36L2 (ZFP36 ring finger protein like 2). PHENOTYPE: Mice expressing decreased levels of an amino-terminal truncated protein display female infertility whereas mice homozygous for a null allele die within two weeks as a result of hematopoietic system defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
