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Protein Coding Gene : Socs5 suppressor of cytokine signaling 5
Primary Identifier  MGI:2385459 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  56468
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables epidermal growth factor receptor binding activity. Involved in several processes, including cellular response to low-density lipoprotein particle stimulus; negative regulation of cytokine production; and regulation of T-helper cell differentiation. Acts upstream of or within epidermal growth factor receptor signaling pathway. Predicted to be located in cytoplasm. Is expressed in retina. Orthologous to human SOCS5 (suppressor of cytokine signaling 5).
PHENOTYPE: Homozygous null mutants are viable and fertile with normal immune system morphology and function. [provided by MGI curators]
  • synonyms:
  • Cish5,
  • MGI:1916302,
  • RIKEN cDNA 1810018L08 gene,
  • 1810018L08Rik,
  • Socs5,
  • SOCS-5,
  • suppressor of cytokine signaling 5,
  • cytokine inducible SH2-containing protein 5
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Disease

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