Primary Identifier | MGI:2685174 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 240185 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of sprouting angiogenesis. Located in cell-cell junction. Is expressed in meninges; tail mesenchyme; and vertebral axis musculature. Orthologous to human JCAD (junctional cadherin 5 associated). PHENOTYPE: Mice homozygous for a knock-out allele show decreased body weight and impaired tumor growth and tumor angiogenesis with no apparent defects in physiological vascular development and permeability. [provided by MGI curators] |