| Primary Identifier | MGI:108460 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 14370 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including PDZ domain binding activity; Wnt receptor activity; and Wnt-protein binding activity. Involved in Wnt signaling pathway. Acts upstream of or within several processes, including T cell differentiation in thymus; canonical Wnt signaling pathway; and positive regulation of JUN kinase activity. Located in plasma membrane. Part of Wnt-Frizzled-LRP5/6 complex. Is active in neuronal dense core vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human FZD8 (frizzled class receptor 8). PHENOTYPE: Homozygous mutation of this gene does not appear to result in a phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
