Primary Identifier | MGI:1925055 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 77805 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; peptide-lysine-N-acetyltransferase activity; and zinc ion binding activity. Predicted to be involved in mitotic sister chromatid cohesion; protein acetylation; and regulation of DNA replication. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer; gonad; reproductive system; and urinary system. Orthologous to human ESCO1 (establishment of sister chromatid cohesion N-acetyltransferase 1). PHENOTYPE: Mouse embryonic fibroblast homozygous for an activated conditional allele exhibit mitotic arrest in G1. [provided by MGI curators] |