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Protein Coding Gene : Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1

Primary Identifier  MGI:1925055 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  77805
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable identical protein binding activity; peptide-lysine-N-acetyltransferase activity; and zinc ion binding activity. Predicted to be involved in mitotic sister chromatid cohesion; protein acetylation; and regulation of DNA replication. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer; gonad; reproductive system; and urinary system. Orthologous to human ESCO1 (establishment of sister chromatid cohesion N-acetyltransferase 1).
PHENOTYPE: Mouse embryonic fibroblast homozygous for an activated conditional allele exhibit mitotic arrest in G1. [provided by MGI curators]
  • synonyms:
  • establishment of sister chromatid cohesion N-acetyltransferase 1,
  • RIKEN cDNA A930014I12 gene,
  • A930014I12Rik,
  • Esco1

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