| Primary Identifier | MGI:95459 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 225207 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein domain specific binding activity. Acts upstream of or within neuron fate commitment. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including bone; branchial arch; central nervous system; embryo mesenchyme; and genitourinary system. Used to study schizophrenia. Orthologous to human ZNF521 (zinc finger protein 521). PHENOTYPE: Mice homozygous for a null allele exhibit postnatal growth retardation, behavioral anomalies including hyperlocomotion, lower anxiety, higher impulsivity and impaired learning, abnormal formation of the neuronal cell layers of the dentate gyrus in the hippocampus, and premature death. [provided by MGI curators] |