| Primary Identifier | MGI:1918269 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 106931 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in brain; foregut; nasal epithelium; and tooth. Used to study scalp-ear-nipple syndrome. Human ortholog(s) of this gene implicated in scalp-ear-nipple syndrome. Orthologous to human KCTD1 (potassium channel tetramerization domain containing 1). PHENOTYPE: Mice homozygous for an ENU-induced point mutation exhibit perinatal lethality while heterozygous mutant mice display kidney dysfunction and secondary effects thereof as the main pathological phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
