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Protein Coding Gene : Dsc3 desmocollin 3
Primary Identifier  MGI:1194993 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  13507
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable calcium ion binding activity and gamma-catenin binding activity. Acts upstream of or within in utero embryonic development. Located in several cellular components, including desmosome; extracellular region; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and skin. Orthologous to human DSC3 (desmocollin 3).
PHENOTYPE: Homozygous null mice die before implantation. Heterozygous mice do not display any gross abnormalities and have normal epidermal development and keratinocyte differentiation. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 5430426I24 gene,
  • desmocollin 3,
  • MGI:1918578,
  • Dsc3,
  • 5430426I24Rik
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Proteins

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Genes --> Homologs

Interactions

3 Pathways

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Phenotype

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Disease

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