Primary Identifier | MGI:1098815 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 52563 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein polyubiquitination. Predicted to be part of anaphase-promoting complex. Is expressed in 4-cell stage embryo; brain; cerebellum; and cerebral cortex. Used to study infertility. Orthologous to human CDC23 (cell division cycle 23). PHENOTYPE: Homozygosity for the p.Y329C mutation leads to female infertility. [provided by MGI curators] |