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Protein Coding Gene : Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3
Primary Identifier  MGI:1201403 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  14587
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables axon guidance receptor activity. Acts upstream of or within axon guidance; neuron migration; and sympathetic nervous system development. Located in external side of plasma membrane. Is expressed in several structures, including adrenal medulla; alimentary system; cranial nerve; ganglia; and genitourinary system. Orthologous to human GFRA3 (GDNF family receptor alpha 3).
PHENOTYPE: Mice homozygous for disruption of this gene display ptosis and poor development of the sympathetic chain ganglia and associated nerves. [provided by MGI curators]
  • synonyms:
  • GFR alpha-3,
  • Gfra3,
  • expressed sequence Y15110,
  • Y15110,
  • GFRalpha3,
  • glial cell line derived neurotrophic factor family receptor alpha 3,
  • MGI:2147424
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