| Primary Identifier | MGI:96245 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 15526 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity. Involved in iron-sulfur cluster assembly; negative regulation of hematopoietic stem cell differentiation; and negative regulation of hemopoiesis. Acts upstream of or within protein export from nucleus. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in early conceptus; germ cell of gonad; heart; and liver. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (Hsp70) member 9). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality while heterozygotes display decreased pre-B cell number. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
