Primary Identifier | MGI:1921252 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 74002 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction. Located in several cellular components, including cleavage furrow; neuronal cell body; and ruffle membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in central nervous system; eye; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human PSD2 (pleckstrin and Sec7 domain containing 2). PHENOTYPE: Mice homozygous for a null allele display a decrease in the density of asymmetric synapses in the middle molecular layer but no cerebellum-related behavioral defects. [provided by MGI curators] |