| Primary Identifier | MGI:1918552 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 71302 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity; phospholipid binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in mitophagy. Predicted to be located in cytosol and endosome membrane. Predicted to be active in mitochondrion. Is expressed in amygdala; diencephalon lateral wall mantle layer; hypothalamus mantle layer; olfactory epithelium; and telencephalon mantle layer. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia and juvenile myelomonocytic leukemia. Orthologous to human ARHGAP26 (Rho GTPase activating protein 26). PHENOTYPE: Mice homozygous for a hypomorphic allele display reduced myofiber size, impaired myoblast fusion and abnormal muscle regeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
