Primary Identifier | MGI:1917890 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 70640 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity; 5'-3' RNA exonuclease activity; and telomerase RNA binding activity. Involved in mRNA catabolic process. Predicted to be located in cell junction; cytoplasmic ribonucleoprotein granule; and nucleoplasm. Predicted to be part of RISC complex. Predicted to be active in P-body. Is expressed in several structures, including eye; genitourinary system; liver; lung; and spleen. Orthologous to human DCP2 (decapping mRNA 2). PHENOTYPE: Mice homozygous for a gene trapped allele are viable and fertile. Mice homozygous for a null allele exhibit male infertility with reduced sperm numbers and motility. [provided by MGI curators] |